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BBB transporters There are a limited number of solutes that can cross the BBB without the use of transporters

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How Dihexa Works (Proposed and Partly Retracted) The proposed mechanism is that Dihexa potentiates hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, downstream of PI3K-AKT, driving dendritic spine formation and synaptogenesis