Immundiagnostik A
Proposed pathways include modulation of multiple neurotransmitter systems (influencing serotonin, dopamine, norepinephrine, GABA, glutamate levels), possible involvement of NMDA receptors, alpha-1 adrenergic signaling (e.g., potentiating pineal acetyltransferase activity), inhibition of somatostatin release via dopaminergic routes, reduced ACTH/cortisol for stress buffering, and stimulated growth hormone or somatoliberin secretion
Those who engage in detrimental habits such as over-consuming alcohol, drugs, or refined sugar, and those who smoke also have an increased need for glutathione
Mechanistic studies to understand the therapeutic effects of glutamate-targeted agents currently in use will inform development of future antidepressant agents
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA