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Furthermore, both GSQs (124) and QQ-protein thiols have been shown to be unstable and transient -lasting for minutes and hours instead of days- suggesting an overestimation of the proposed in vitro toxicity (125)

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According to magnetic resonance spectroscopy, the concentration of glutathione increased in the brain as well, but this trend was not significant

This model using hCMEC/D3 favored ECD, by decreasing cell proliferation, increasing caspase 3/7 levels, inducing apoptosis, increasing oxidative phosphorylation, inducing mitochondrial dysfunction, and promoting higher cell migration [115]

Residue Lys105 of ScGrx7 is conserved in many glutaredoxins 3,11,12,19 (r 1 in Fig