However, in OA, M2 numbers are limited and may shift toward an M1-like phenotype under sustained inflammatory stimuli, reducing their capacity to maintain iron homeostasis (109, 110).Together, these insights support the hypothesis that iron metabolism in M1 macrophages not only contributes to ferroptosis susceptibility in OA, but also represents a potential immunometabolic checkpoint for therapeutic intervention
HongJKimMHongJNohHParkKLeeMet alIn vivo quantitative analysis of advanced glycation end products in atopic dermatitis-possible culprit for the comorbidities
Sulfated glycosaminoglycans in decellularized placenta matrix as critical regulators for cutaneous wound healing
Clinical outcomes and long-term efficacy of high tibial osteotomy in treating knee instability: an updated systematic review
Michelet F, Gueguen R, Leroy P, Wellman M, Nicolas A, Siest G