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In the second experiment, discussed in the previous section, Campbell eliminated the highest-dose group, but kept the next two highest doses which had killed one and four out of twelve animals in the preliminary study

This evidence collectively suggests a dynamic compensatory relationship between the two pathways: inhibiting one cell death mechanism may lead to the activation of the other as compensation

NOS uncoupling results in reduced synthesis of NO and enhances the capability of the enzyme to produce ROS [67]

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