Role in Chronic Disease Prevention: Evidence suggests that higher glutathione levels are associated with a reduced risk of chronic illnesses, such as heart disease and diabetes (Smith et al., 2020)
Anthonymuthu TS, Tyurina YY, Sun WY, Mikulska-Ruminska K, Shrivastava IH, Tyurin VA, et al
These isoforms are able to effectively combat reactive nitrogen species, such as NO2 and peroxynitrite, due to this structural feature
Each of these compounds works through defined receptor-mediated mechanisms, each has a distinct evidence base, and each requires clinical context to use appropriately
Finally, frequency of GSTP1 aberrant methylation in diffuse large B-cell lymphoma (DLBCL) also led to studies to validate the prognostic impact of such epigenetic alteration in these lymphomas