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Characterizing human stem cell-derived sensory neurons at the single-cell level reveals their ion channel expression and utility in pain research

Lun et al

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By its upstream action of inhibiting lipid peroxidation, GPX4 can indirectly but effectively reduce the expression levels of these destructive enzymes, thereby delaying or preventing ECM breakdown (Xiao et al., 2024) (Figure 1)

The Journal of Clinical Endocrinology & Metabolism, 89(2), 936939