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Epigenetic Modification Epigenetic mechanisms have been reported to be associated with the pathogenesis of CVD

While choline does not compete with other nutrients for enterocyte transport, gut microbes can limit its bioavailability ( Escherichia coli , Pseudomonas aeruginosa , and Acinetobacter baumannii , choline uptake is mainly mediated by the BetT transporter, whose expression and transport activity are upregulated by hyperosmotic stress ( Figure 2 )

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