341 PGC-1 expression elicits an obvious decrement in the migratory capacity of PC3 and DU145 cells and a robust anti-invasive phenotype, but ERR deletion abolishes the induction of target genes of the transcription factor upon induction of PGC-1
Third, the data of Figure 4 show fold-changes compared to wild-type: even if strongly induced at the protein level, low abundance enzymes may not make a marked contribution to GSH oxidation within the cellular context
It appears to do this through several mechanisms including upregulation of growth factors involved in mucosal repair, reduction of inflammatory mediators, and support of gut barrier integrity
doi: 10.3389/fpls.2018.00751 Received 15 February 2018 Accepted 16 May 2018 Published 07 June 2018 Volume 9 - 2018 Edited by Kendal Hirschi, Baylor College of Medicine, United States Reviewed by Toshiro Shigaki, The University of Tokyo, Japan
(e) should not generate any immunological response