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When evaluating adipose tissue in WT and 3-KO mice, researchers found that neither treatment significantly affected white adipose tissue mass in either genotype
"UMEM Educational Pearls - University of Maryland School of Medicine, Department of Emergency Medicine"
This helped to show that NNMT is a key target in metabolic research. Neelakantan and colleagues then expanded research involving small-molecule NNMT inhibitors
SLU-PP-332 distribution The distribution pattern of SLU-PP-332 is characterized by: Rapid and extensive distribution to target tissues High volume of distribution, indicating good penetration into various body compartments Potential for crossing the blood-brain barrier, expanding its therapeutic potential These distribution characteristics may contribute to the versatility of SLU-PP-332 in treating various conditions
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