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GSSG prevented TNF-induced activation of IKK-, an upstream kinase in the NF-B signaling pathway, by inducing IKK- glutathionylation (IKK--SSG formation)

Future studies should investigate the combined use of ferroptosis inhibitors with other therapies, such as anti-inflammatory drugs and immunomodulators, to enhance treatment effectiveness

from Johns Hopkins University, School of Medicine under the mentorship of Bert Vogelstein and did her post-doctoral work with Lewis Cantley at Weill Cornell Medicine

To validate the score, we confirmed that it was associated with PCOS in women in the UK Biobank ( P = 9 10 27 ) and that the odds of PCOS increased across increasing quintiles of the PRS (Supplementary Fig

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