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showed that markers of an impaired barrier function associated with bacterial translocation as LPS and LBP are increased in the serum of CD patients with active and inactive disease whereas they are only increased in UC patients with active disease

This was attributed to the thickness of the porcine ear skin

Upon ligand interaction, these regions undergo a Venus flytrap-like conformational closure, ensuring high-affinity binding and precise gating of the receptor channel (Lam et al

Be direct about what you know, what you don't, and the review timeline

Disclosure of interest: Dr Natalie Fini: nothing to disclose