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The primary resistance mechanisms include mutations in FCY2 , encoding cytosine permease (which mediates drug uptake), and mutations in FCY1 , encoding cytosine deaminase (required for 5-FC activation) (Longley et al., 2003
HYDROCODONE BITARTRATE AND ACETAMINOPHEN - hydrocodone bitartrate and acetaminophen tablet Eywa Pharma Inc ---------- WARNING: SERIOUS AND LIFE-THREATENING RISKS FROM USE OF HYDRCODONE BITARTRATE AND ACETAMINOPHEN TABLETS Addiction, Abuse, and Misuse Because the use of Hydrocodone Bitartrate and Acetaminophen Tablets exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death, assess each patients risk prior to prescribing and reassess all patients regularly for the development of these behaviors and conditions [see WARNINGS]
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