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How are B12 shots administered, and is the process painful

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Dark controls and a validated chemical actinometric system or calibrated radiometer should also be applied

Subjects may have difficulty in getting off to sleep and may experience restless legs syndrome, sudden muscle jerks (myoclonus) just as they are dropping off or be jolted suddenly by a hallucination of a loud bang (hypnagogic hallucination) which wakes them up again