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binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302)
Catalogue Numbers: AF6212-100
Bioworld Molecular Weight: ~25 kDa
The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth
Background: High mobility group (HMG) chromatin proteins bind to the minor groove of AT-rich DNA sequences with high affinity
CNOT1 Polyclonal Antibody-BS78714 Microglial Cells binding to unmodified histone H3CNOT1 Polyclonal Antibody Product: 1mg ml in PBS with 0. 02% sodium azide, 50% glycerol, pH7. 2 Sizes: 50l, 100l Catalogue Numbers: BS78714 50, BS78714 100 Swiss Prot: A5YKK6 Host: Rabbit CNOT1 Polyclonal Antibody BS78714 Storage and Stability: Store at 4C short term. Aliquot and store at 20C long term. Avoid freeze thaw cycles. Reactivity: Human, Mouse Applications: WB, IF ICC All Applications: WB,1: 200 1: 2000 IF ICC,1: 50 1: 200 Background: