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Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1186/s13020-026-01340-0

186 , 125141 (2021) Mukherjee, S., Ghosh, S., Choudhury, S., Gupta, P., Adhikary, A., Chattopadhyay, S.: Pomegranate polyphenols attenuate inflammation and hepatic damage in tumor-bearing mice: crucial role of NF-B and the Nrf 2 /GSH axis

however, the characteristics of the tinnitus, presence of depression, and ratings of quality of life and overall health were unchanged

For validation we used venous blood of five healthy donors