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Further advances in bioinformatics-driven aptamer design, in silico SELEX methods, and next-generation aptamer technologies, such as SOMAmers and X-aptamers, are foreseen to result in enhanced therapeutic efficacy and broader clinical use against cancer and other diseases

Unlike NSAIDs, acetaminophen works primarily in the brain and spinal cord rather than throughout the body, which explains why it's effective for pain and fever but doesn't reduce inflammation like NSAIDs do (Li et al., 2013

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[PubMed: 2405702] 90