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A synthetic compound called carbonyl cyanide-m-chlorophenyl hydrazone (CCCP) was found to act as a decoupler that disrupts the proton motive force of the pump, resulting in an antibiotic-potentiating effect with tetracycline against Helicobacter pylori and Klebsiella , alleviating gastrointestinal tract-associated diseases 82,83

doi: 10.1038/cdd.2014.150 15 GuYHanJJiangCZhangY

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This likely reflects the additive gastrointestinal effects of combining two separate appetite-suppressing compounds