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Age-matched subgroup analysis demonstrated a significant increase in emphysema in marijuana (93%) patients, compared to tobacco-only smokers (66%), as well as a significant increase in the proportion of paraseptal emphysema (versus other types) in marijuana smokers (53%), when compared to both tobacco-only smokers (24%) and control groups (7%)

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Mio T, Romberger DJ, Thompson AB, Robbins RA, Heires A, Rennard SI: Cigarette smoke induces interleukin-8 release from human bronchial epithelial cells

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