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Recent studies with animal models provide evidence that pheomelanin pigment pathway is implicated in UV radiation-independent carcinogenic contributions to melanomagenesis by mechanisms of oxidative damage 6,7,8 Two non-exclusive hypotheses were proposed to define pheomelanins pro-oxidant activity: (i) the pigment promotes the formation of damaging ROS and (ii) the pigment depletes protective antioxidants (e.g., glutathione) 9,10
Acne usually develops due to a combination of factors, including: Excess sebum (oil) production Clogged hair follicles Growth of acne-causing bacteria Hormonal fluctuations Inflammation Genetic predisposition Since glutathione does not directly influence these main causes, it is unlikely to be responsible for acne in most people
"Extracorporeal Shock Wave Therapy for Chronic Painful Heel Syndrome: A Prospective, Double-Blind, Randomized Trial." Journal of Bone and Joint Surgery , 2007
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