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Cellular strategy Cellular strategy-mediated brain-targeted delivery strategy is an innovative approach that utilizes natural cells or their derived carriers (such as exosomes, cell membrane vesicles) as drug delivery vehicles to efficiently cross the BBB and target drugs to brain tissues

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On the other hand, the MUC5AC promoter has a B cis-element, which reduces the activity of the promoter and lowers expression (Perrais et al., 2014)