FIGURE 4 To overcome this limitation, numerous high-throughput screening efforts to identify CBS inhibitors have been conducted, but a truly CBS-selective compound has yet to be discovered (Sasaki et al., 2023)
Uversky VN, Oldfield CJ, Dunker AK (2008) Intrinsically disordered proteins in human diseases: introducing the D 2 concept
This process can send the cell into a downward tailspin, whereby the cell is even more susceptible to free radical stress, and eventually, this process can end up creating a runaway neurotransmitter response
Kahn MJ, Maley JH, Lasker GF, Kadowitz PJ
A priori inclusion criteria and duplicate screening decreased the risk of bias