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The somatotropic axis begins with the release of two hormones called growth hormone-releasing hormone (GHRH) and ghrelin

The intercellular junction serves as the primary channel through which water and other solutes traverse the vascular endothelium

Despite differing etiologies, they share a few pathophysiologic mechanisms such as oxidative stress, hair cycle dysregulation, and impaired follicular keratinocyte and dermal papilla cell proliferation [2,3,4]

Omega-3 fatty acids, mainly from fish oil, are frequently used due to their role in brain development and inflammation reduction

Thus, our data suggest that in the experimental periodontitis model that we applied ( i.e