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10.1038/s44220-023-00145-6 232 KelmendiB.AdamsT

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lactis on whey substrate (Sybesma et al

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Folic acid significantly reduced MDA level, protein carbonyl content, Bax, the caspase-3 mRNA, and protein expression levels in the cerebellum of Hcy-treated group

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Safety data indicate mostly mild gastrointestinal events (nausea, diarrhea, vomiting), dose-dependent, and often improved with titration

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Rational targeting of GPX1, GPX4 and TXNRD1 holds high therapeutic potential in different pathological settings, where lipid peroxidation is either harmful or can be triggered for therapeutic purpose, as it is the case in numerous cancers and more particularly AML

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