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Coso has received speaker or consulting fees from AstraZeneca, Boehringer Ingelheim, Chiesi, GlaxoSmithKline, Menarini, Novartis, Sanofi and TEVA, and research grants from Menarini, AstraZeneca and Boehringer Ingelheim

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1 Introduction More fundamental than asthma, yet with limited understanding, mitochondrial defects or dysfunction may play a pivotal role in driving inflammation and/or injury, potentially serving as a common mechanism in the progression of inflammatory lung diseases (Zhou et al., 2021)