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Arch Biochem Biophys 423:6673 Palamara AT, Perno CF, Aquaro S, Bue MC, Dini L, Garaci E (1996) Glutathione inhibits HIV replication by acting at late stages of the virus life cycle

The peptide may appear clear and unchanged, but receptor binding affinity decreases as the tertiary structure denatures

All three engage the same receptor the GHRH receptor on pituitary somatotroph cells but each takes a structurally distinct approach to extending the practical research half-life of native GHRH