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These beneficial effects may additionally be mediated via the 7 nicotinic receptor as this receptor subtype also enhances the antidepressant effects of serotonin uptake blockers ( Finally, nicotine replacement therapy (NRT, with gum, transdermal patch, intranasal spray and inhaled and oral preparations) has high-quality evidence that all of the licensed forms of NRT support people who want to quit smoking

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Important evidence for this concept came from depletion studies in which DCs were selectively eliminated during ongoing allergic inflammation in the lung

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