doi: 10.1016/j.nutres.2014.09.007
Lin Yuan, DongYan Song, and JiaYi Li conceived and edited the manuscript
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By midlife, NAD+ can drop by 50%, exacerbated by inflammation and lifestyle.[14] Factors like poor diet, sedentary behavior, or chronic stress further deplete NAD+ by activating consuming enzymes, creating a vicious cycle
The researchers suggested that this allows for a rapid response to injury while preventing the adverse effects of an sustained inflammatory state