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A 2021 Nature Communications study then showed that MOTS-c is induced by exercise and that treating mice, including animals started late in life, boosted running capacity and physical performance across young, middle-aged, and old groups [3]

HA may exert a chondroprotective effect through anti-inflammatory properties and improved joint lubrication, while AOD9604 may activate developmental pathways that support cartilage regeneration

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The muscle-preserving effects of the compound complement the muscle-building stimulus of weight training

Linear growth, expressed as centimetres and height for age z-score (HAZ), and weight expressed as kilograms, weight for age (WAZ) and weight for height (WHZ) will be compared between the study groups