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Cellular immunity plays a central role, with Th1 and Th17 T-helper cells, autoreactive T cells, and B lymphocytes infiltrating the gland, recruiting neutrophils, macrophages, plasma cells, and CD8 + cytotoxic T cells, leading to follicular epithelial destruction

After each experimental run, CCD images were analyzed frame-by-frame to determine the freezing temperature of each nucleation event, determined by the opacity of the droplet, where liquid droplets were transparent and frozen droplets were opaque

The Wolverine protocol is administered as subcutaneous injections

Prasad, O