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In the US, the Centre for Disease Control and Prevention (CDC) calculates that a little over 16 million Americans are living with a disease that is directly caused by smoking

All authors contributed to and have approved the final manuscript

Tobacco use is the leading preventable cause of miscarriage, stillbirth and neonatal deaths, and evidence has shown that health effects extend into childhood

You need to remind yourself that you are making a big change to your life and need to take the time to prepare along the way

The widest variation occurs in 1997, where the LOO range spans from -30.6 to -18.0 (a 12.6-pack spread), likely driven by removing Nevada (the second-largest weighted state)