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Recommended to cycle (3) months on, (1) month off

Potentiation of opioid analgesia in dopamine2 receptor knock-out mice: evidence for a tonically active anti-opioid system

10.1055/s-2001-15105 339

This approach effectively lowers inflammatory factor expression levels following PEID, alleviates postoperative low back and leg pain symptoms, reduces hospital stay duration, and accelerates recovery