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Xiong S, Liao L, Chen M, Gan Q

In both AID patients and corresponding animal models, the expansion and accumulation of MDSCs protect host tissues from damage caused by excessive T cell responses by inhibiting T cell activation and immune reactions (102, 119), This further indicates that MDSCs may exert a detrimental impact on immune responses by modulating the functions of CD4 + and CD8 + T cells, thereby contributing to the pathological processes of AIDs

These risks are exactly why an intramuscular injection is safer given by a trained clinician than self-administered at home

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During an IV therapy procedure, substances are administered into the body through the veins, delivering fluids directly into the veins using a pump or gravity to ensure controlled infusion