Despite the primary injury due to mechanical force, diffuse and multifocal damage often appears, leading to diffuse axonal injury by blunt force of shearing, tearing, and stretching of the axon and further damage of the long-distance white matter connection, with large-scale network disconnection as the core mechanism of cognitive impairment
Blemish-free skin Natural-looking skin Health and Wellness Benefits Liver and kidney detoxification
These enzymes play a crucial role in combating NAPQI-induced oxidative stress by scavenging ROS and restoring cellular redox balance
Brown TC, Tran IC, Backos DS, Esteban JA (2005)
Importantly, the application of ferrostatin-1 successfully mitigated the ferroptosis and EMT-related dysfunctions, indicating promising pathways for therapeutic intervention ( Tumor protein p53 (TP53) , Enhancer of Zeste Homolog 2 (EZH2 ), Tissue inhibitor matrix metalloproteinase 1 (TIMP1) , Solute carrier family 3 member 2 (SLC3A2), and Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) (Zeng et al., 2025)
