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In eight studies in which the effects of smoking cessation on endothelial function were assessed by biomarkers[19, 20, 23, 24, 30, 31, 92, 93], five studies showed that smoking cessation increased or improved biomarkers for endothelial function including circulating levels of nitrate/nitrite, NO, vvWF, ICAM-1, EPCs and EMPs and activity of eNOS [19, 23, 24, 30, 31]

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Myth 2: Secondhand smoke has little health hazards Secondhand smoke contains a large number of harmful substances and carcinogens, and children are more sensitive to secondhand smoke

To further investigate this role for S100A8/A9, we deleted S100A8 with CRISPR/Cas9

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