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Cotinine assays provide an objective quantitative measure that is more reliable than smoking histories or counting the number of cigarettes smoked per day

These include heart disease, high blood pressure, stroke, and Type 2 diabetes

After mating, females were further exposed for 7 days/week, up to 3 weeks after delivery, with the exception of the first 5 days of lactation

That means nicotine extracted from a tobacco leaf and nicotine synthesized in a lab are ultimately the same molecule when produced at high purity

Vape cartridges allow vaping liquids based on nicotine salts, which have a higher bioavailability, compared to e-liquids based on pure nicotine