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With regard to function, most NLRPs are involved in immune and inflammatory responses by means of the assembly of a multiprotein platform known as the inflammasome (59)

Administration of CB-1158 (a small molecule inhibitor of arginase) can slow tumor growth rates, block myeloid cell-mediated suppression of T-cell proliferation, and increase the number of tumor-infiltrating CD8 + T cells and NK cells in mouse models of multiple tumors

Role of the gut microbiota in nutrition and health

doi: 10.2337/db07-1403