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In order to quit, a plan needs to be in place to help with the triggers that will inevitably happen, causing a person to struggle with quitting

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Total daily nicotine uptake Since humans differ widely with respect to the metabolism of nicotine to cotinine and subsequent elimination of cotinine, the use of cotinine as a marker of nicotine uptake has been questioned

Most importantly, cMRTPs, like any other tobacco product, should never be sold to underage individuals

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