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doi: 10.1038/s41584-022-00827-y

Damage-associated molecular patterns (DAMPs) are of particular interest, as they can trigger the inflammatory response observed in the active stage of vitiligo, with a series of DAMP-associated proteins existing in vitiligo.4 The DAMP with the most evidence of association with vitiligo is heat shock protein 70 (HSP70), which belongs to the family of intracellular chaperones whose function is to prevent incorrect protein folding