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To confirm that LaccID labeling depends on O 2 , we depleted O 2 from the labeling mixture with glucose oxidase, which consumes O 2 upon oxidation of its substrate glucose 31

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Caenorhabditis elegans proteins that localized to the cytoplasm or nucleus across multiple tissues, demonstrating the feasibility of in vivo tissue-specific mapping of organelles (Reinke et al., 2017b)

Other commonly reported effects include water retention or puffiness, tingling or numbness in the hands (a GH-related effect), a brief head-rush or flushing, and tiredness