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GPs normally give these every 12 weeks, but the effects wear off before this and as a result the patient is left feeling sluggish and run down

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Skin Laxity and Collagen Disruption GLP-1 receptor agonists like semaglutide and tirzepatide produce weight loss at a rate that routinely outpaces the skin's adaptive capacity

Toxic doses in research have been measured at 300-3,750 times higher than therapeutic ranges, providing substantial safety margins