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10.1016/j.chmed.2023.05.001 24 ChenW

The main disadvantages include potential gastrointestinal upset (nausea, vomiting, diarrhoea), particularly when starting oral supplements

Table 3 reports the evaluation of pyroglutamic acid in a nonclinical study of APAP-induced hepatotoxicity (Sun et al

In a series of experiments on humans and mice, the researchers found that L-carnitine is broken down by gut bacteria to produce trimethylamine-N-oxide (TMAO), which previous research has linked to heart and artery damage

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