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Cellular Senescence and Aging Research Senescent cells accumulate naturally with age and contribute to: Chronic inflammation Tissue dysfunction Reduced regenerative capacity Biological aging Research involving FOXO4-DRI investigates its potential role in selectively clearing these dysfunctional cells to support healthier tissue environments

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21 It is also possible that this lesion represents a response to inflammation at a distant site, as it is similar to the lesion of nonspecific reactive hepatitis associated with chronic extrahepatic disease

The tea is measured with a bamboo spoon, or shashaku, into a heated tea bowl known as a chawan