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Its secreted hemolysins and exotoxins directly damage tissue and trigger inflammation 131

However, stability can be highly sensitive to environmental conditions, where exposure to salts or extreme pH may compromise stability and promote aggregation

Giving intraoperative intravenous magnesium sulfate, 50 mg/kg loading dose followed by 15 mg/kg/hour, reduces the onset time of rocuronium, enhances its clinical effects, reduces the dose of intraoperative opiates, and prolongs the spontaneous recovery time