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Indeed, in the case of the peroxiredoxin Mt AhpE, the reactivity of the persulfidated protein was higher than that of the thiol protein in the case of a non-specific electrophile, but lower in the case of the specific hydroperoxide substrates ( The higher acidity of LMW persulfides versus thiols could lead one to think that, in the case of a protein, a negative charge would appear upon persulfidation

p53 transcriptionally activates the expression of GLS2 (Jennis et al., 2016) and SAT1 (Ou et al., 2016) (a polyamine catabolic enzyme) and transcriptionally represses SLC7A11 (Jiang et al., 2015)

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BPC-157 is classified as a chemical reagent approved for research purposes but not as a food product, drug, or dietary supplement

None of the 18 drugs were shown to form specific interactions with ARG50 in 1GP1, however 5 of 18 drugs, including atenolol (Fig