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Because drugs that increase dopamine have the potential for abuse, Volkows report concluded, these results suggest that risk for addiction in vulnerable persons merits heightened awareness. (Cephalon, in a response to the report, notes that Provigils label urges physicians to monitor patients closely, especially those with a history of drug abuse.) On the Web site Erowid, where people vividly, and anonymously, report their experiences with legal and illegal drugs, some modafinil users have described a dependency on the drug

Published 2023 May 25

Peroxynitrite is capable of inducing lipid peroxidation and nitrosation of many tyrosine molecules that normally act as mediators of enzyme function and signal transduction [19]