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Therapeutic Medicine 20 (2), 10031011

GHK-Cu Peptide & Barrier Integrity (Preclinical Research) In a mouse model of DSS-induced ulcerative colitis, researchers observed that GHK-Cu influenced cellular signaling pathways related to barrier integrity, including: Tight junction protein expression SIRT1/STAT3 signaling pathways While this study was preclinical and not cosmetic-focused, it reinforced something researchers have long suspected: GHK-Cu interacts with fundamental cellular repair processes, not just surface-level skin processes [1]

For that reason, glutathione injections work best when paired with treatments that target the skin directly

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Involvement of vasopressin and corticotropin-releasing hormone in VIP- and PHI-induced secretion of ACTH and corticosterone