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Abstract One of the biochemical abnormalities found in diabetic tissues is a decrease in the cytosolic oxidized to reduced forms of the nicotinamide adenine dinucleotide ratio (NAD + /NADH also known as pseudohypoxia) caused by oxidation of excessive substrates (glucose through the polyol pathway, free fatty acids and lactate)

L-Glutathione l dng kh ca Glutathione v cng l nguyn liu tng hp Glutathione

doi: 10.3389/fcvm.2021.602086 150

Lysosomal pH, lysosomal ferrous ions, and lipid peroxidation were visualized, revealing that acidity restoration released trapped iron within lysosomes and reactivated ferroptosis

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