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Device quality, needle depth precision, practitioner training, and protocol fidelity all determine outcomes

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Epidermal melanocytes, owing to their specialized role in melanin synthesis, exhibit a heightened susceptibility to elevated ROS production, a phenomenon accentuated by solar exposure during the tanning process and instances of inflammation, subsequently culminating in post-inflammatory hyperpigmentation 17

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Suarez E P, Pugliese S, Galdiero E, Guida M, Libralato G, Saviano L, Spampinato M, Pappalardo C and Siciliano A 2023 Multigenerational test on Daphnia spp.: A vision and new perspectives