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Common signs of B12 deficiency include fatigue, weakness, constipation, loss of appetite, and weight loss (NIH, 2020)

You may be vitamin B deficient if you experience some or all of the following unexplained symptoms: Skin cracks around the mouth Scaly lip skin Skin rashes Fatigue Anemia Depression or irritability Confusion Diarrhea or constipation Abdominal cramps Tingling or numbness in your feet and hands Vitamin B12 deficiency is particularly serious, as it increases your risk for neuropsychiatric disorders

Maternal Serum Vitamin B12 during Pregnancy and Offspring Autism Spectrum Disorder. Nutrients 15.8 (2023): 2009

It is important to monitor and adjust intake accordingly to support cellular health

Record all handling procedures, including reconstitution volume, date, and storage conditions, in your laboratory notebook for future reference and reproducibility